Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649930 | 0.95 | NAAA (0.41) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL26940466 | 0.80 | CA2 (0.47) | NAAACA2MAPK1PTGESALOX5 | |
| SCHEMBL5528479 | 0.78 | NAAA (0.47) | NAAACA2MAPK1 | |
| SCHEMBL9344140 | 0.75 | PDE4D (0.38) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8661247 | 0.74 | CYP2C19 (0.41) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL4100097 | 0.73 | CA2 (0.38) | CA2MAPK1PTGESALOX5PPARG | |
| SCHEMBL9345699 | 0.72 | NAAA (0.33) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9806439 | 0.72 | NAAA (0.61) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL10551706 | 0.71 | NAAA (0.36) | NAAAPDE4D | |
| SCHEMBL18974981 | 0.71 | NAAA (0.69) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5275756-A | Pyrimidine ether compounds for electrooptical elements | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0469893-A1 | Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof | Takasago International Corporation (JP) | 1992-02-05 | — | — | EP | disclosed |