Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269795 | 0.80 | NLRP3 (0.36) | ALDH1A1 | |
| SCHEMBL13879174 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL10211081 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL13879188 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL13879079 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL9270300 | 0.73 | TOP2A (0.36) | — | |
| SCHEMBL7590243 | 0.72 | CYP1A2 (0.63) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL20211423 | 0.71 | SMN1; SMN2 (0.60) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL9628898 | 0.70 | ALDH1A1 (0.57) | ALDH1A1TDP1LMNACYP1A2PPARG | |
| SCHEMBL9629121 | 0.70 | ALDH1A1 (0.57) | ALDH1A1TDP1LMNACYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604483-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | claimed |
| WO-1993006235-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES | ZENECA LIMITED (GB) | 1993-04-01 | — | — | WO | claimed |