Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934552 | 0.94 | CHRM2 (0.51) | PPARGPPARAEPHX1CHRM2CHRM1 | |
| SCHEMBL30487710 | 0.90 | CHRM2 (0.52) | EPHX1CHRM2CHRM1CHRM3CNR1 | |
| SCHEMBL5724443 | 0.90 | CHRM2 (0.52) | EPHX1CHRM2CHRM1CHRM3CNR1 | |
| SCHEMBL17261637 | 0.87 | FFAR1 (0.56) | PPARGPPARAHDAC1HDAC6CHRM2 | |
| SCHEMBL17261656 | 0.84 | HDAC1 (0.54) | PPARGPPARAHDAC1HDAC6CHRM2 | |
| SCHEMBL15818310 | 0.83 | FFAR1 (0.57) | PPARGPPARAHDAC1HDAC6CHRM2 | |
| SCHEMBL934358 | 0.82 | FAAH (0.51) | PPARAHDAC1HDAC6EPHX1FAAH | |
| SCHEMBL6232367 | 0.82 | CHRM2 (0.50) | PPARGPPARACHRM2CHRM1CHRM3 | |
| SCHEMBL12040546 | 0.82 | PPARG (0.52) | PPARGPPARACHRM2CHRM1CHRM3 | |
| SCHEMBL934608 | 0.81 | HDAC1 (0.72) | HDAC1HDAC6CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |