Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344784 | 0.97 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7775666 | 0.76 | ABCB11 (0.31) | ALDH1A1 | |
| SCHEMBL9343779 | 0.72 | EHMT2 (0.32) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7027396 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL2266459 | 0.67 | — | — | |
| SCHEMBL3630263 | 0.67 | — | — | |
| SCHEMBL27868425 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL9730896 | 0.65 | — | — | |
| Bromide SCHEMBL3053670 | 0.65 | — | — | |
| Fluoride Ion SCHEMBL7027242 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439745-B1 | Process for the preparation of 2-chloro-5-methyl-pyridine | BAYER AG (DE) | 1994-08-03 | — | — | EP | claimed |
| EP-0439745-A2 | Process for the preparation of 2-chloro-5-methyl-pyridine | BAYER AG (DE) | 1991-08-07 | — | — | EP | claimed |
| EP-0439745-B1 | Process for the preparation of 2-chloro-5-methyl-pyridine | BAYER AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0439745-A2 | Process for the preparation of 2-chloro-5-methyl-pyridine | BAYER AG (DE) | 1991-08-07 | — | — | EP | disclosed |