Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32683934 | 0.90 | L3MBTL1 (0.43) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL4087213 | 0.87 | ALDH1A1 (0.48) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27351255 | 0.85 | ALDH1A1 (0.47) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL13573000 | 0.85 | CYP2D6 (0.46) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL31547066 | 0.85 | CYP2D6 (0.46) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL3917565 | 0.84 | TSHR (0.48) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL21807114 | 0.84 | ALDH1A1 (0.46) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL9588848 | 0.83 | TP53 (0.44) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL1245676 | 0.82 | CYP2D6 (0.60) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 | |
| SCHEMBL888438 | 0.82 | ALDH1A1 (0.44) | ALDH1A1NPSR1TSHRCYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125414-B2 | Pyridine derivatives compounds for controlling invertebrate pests | BASF SE (DE) | 2015-09-08 | — | — | US | disclosed |
| EP-2451804-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2014-04-30 | — | — | EP | disclosed |
| US-8710056-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2451808-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2456308-A2 | PYRIDINE DERIVATIVES FOR CONTROLLING INVERTREBATE PESTS | BASF SE (DE) | 2012-05-30 | — | — | EP | disclosed |
| US-20120122681-A1 | Pyridine Derivatives Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2451804-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| EP-2451808-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| WO-2011009804-A2 | PYRIDINE DERIVATIVES COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011003796-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011003793-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122681-A1 | Pyridine Derivatives Compounds for Controlling Invertebrate Pests | PRXL2A, GRIN2A, CNR2 | ALDH1A1 1692/4885NPSR1 581/4885TSHR 2414/4885 |
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | CNR2, GRIN2C, GRIN2A | ALDH1A1 2558/4885NPSR1 251/4885TSHR 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.