SCHEMBL9344482

SCHEMBL9344482

CCCCSc1ccc(C(C)(C)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
AR P10275 2/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
SLC2A1 P11166 1/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.39
CA2 P00918 2/20 0.38
PLK1 P53350 4/20 0.38
XDH P47989 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058481 0.85 MAOA (0.50) MAOAMAOBARTHRATHRB
SCHEMBL5887468 0.82 MAOA (0.62) MAOAMAOBARTHRATHRB
Cyanide SCHEMBL28096799 0.80 MAOA (0.46) MAOAMAOBARTHRATHRB
SCHEMBL16301153 0.79 NPC1 (0.47) MAOAMAOBARTHRATHRB
SCHEMBL15086078 0.78 THRA (0.47) MAOAMAOBTHRATHRBALDH1A1
SCHEMBL7260296 0.76 MAOA (0.62) MAOAMAOBARTHRATHRB
SCHEMBL4399477 0.76 MAOA (0.53) MAOAMAOBARTHRATHRB
SCHEMBL21574533 0.76 MAOA (0.43) MAOAMAOBARTHRATHRB
SCHEMBL10525993 0.76 SLC2A1 (0.62) MAOAMAOBARTHRATHRB
SCHEMBL25557817 0.75 SLC2A1 (0.49) MAOAMAOBTHRATHRBSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0328643-B1 (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION TERUMO CORP (JP) 1994-07-06 EP disclosed
US-5043142-A Measuring peroxide-active substances TERUMO KABUSHIKI KAISHA (JP) 1991-08-27 US disclosed
EP-0328643-A1 (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION TERUMO KABUSHIKI KAISHA (JP) 1989-08-23 EP disclosed