Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343725 | 0.90 | NPC1 (0.43) | MTNR1BPREPCHRM4HPGDSMN1; SMN2 | |
| SCHEMBL9348370 | 0.88 | FKBP1A (0.43) | KDM1APOLBHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9343742 | 0.76 | MTNR1B (0.36) | MTNR1BPREPCHRM4NPC1RAB9A | |
| SCHEMBL9344141 | 0.70 | HTR2C (0.49) | PREPHPGDSMN1; SMN2 | |
| SCHEMBL8923231 | 0.68 | POLB (0.51) | MTNR1BCHRM4DRD2HTR7POLB | |
| SCHEMBL9345600 | 0.65 | PREP (0.36) | MTNR1BPREP | |
| SCHEMBL9557081 | 0.65 | NPC1 (0.60) | DPP4HTR7POLBTSHRSMN1; SMN2 | |
| SCHEMBL4412361 | 0.65 | CHRM2 (0.44) | PREPCHRM4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9557071 | 0.64 | NPC1 (0.58) | NPC1RAB9A | |
| SCHEMBL22089300 | 0.64 | HRH3 (0.46) | CHRM4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |