Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343742 | 0.89 | MTNR1B (0.36) | PREPMTNR1BMTNR1A | |
| SCHEMBL9344193 | 0.84 | SLC6A9 (0.43) | MTNR1BMTNR1ASLC6A9PIN1PDE10A | |
| SCHEMBL9348177 | 0.77 | SLC6A9 (0.41) | MTNR1BMTNR1ASLC6A9PIN1PDE10A | |
| SCHEMBL9509654 | 0.74 | MTNR1A (0.45) | MTNR1BMTNR1ASLC6A9PIN1 | |
| SCHEMBL9344645 | 0.65 | MTNR1B (0.37) | PREPMTNR1B | |
| SCHEMBL5730598 | 0.64 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL5731443 | 0.64 | KMT2A (0.41) | — | |
| SCHEMBL10708500 | 0.64 | CACNA1B (0.38) | — | |
| SCHEMBL10514561 | 0.62 | MAPT (0.50) | — | |
| SCHEMBL10709736 | 0.62 | RYR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |