Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.64 |
| ▸ | CA2 | P00918 | 11/20 | 0.64 |
| ▸ | CA4 | P22748 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904295 | 0.94 | CA1 (0.61) | CA1CA2CA4KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10902215 | 0.87 | CA1 (0.54) | CA1CA2CA4KCNH2ALDH1A1 | |
| SCHEMBL3093075 | 0.81 | CA1 (0.68) | CA1CA2CA4ALDH1A1 | |
| SCHEMBL13589983 | 0.81 | CA1 (0.68) | CA1CA2CA4ALDH1A1 | |
| SCHEMBL10898805 | 0.81 | KCNH2 (0.57) | CA1CA2CA4KCNH2ALDH1A1 | |
| SCHEMBL8664094 | 0.80 | KCNH2 (0.60) | KCNH2ALDH1A1 | |
| SCHEMBL9309122 | 0.80 | CA1 (0.71) | CA1CA2CA4ALDH1A1 | |
| SCHEMBL1554845 | 0.80 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPT | |
| SCHEMBL9162085 | 0.80 | CA1 (0.68) | CA1CA2CA4ALDH1A1 | |
| SCHEMBL8385774 | 0.79 | RAB9A (0.62) | ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415557-B1 | Separation of anti-metal chelate antibodies | HYBRITECH INC (US) | 1994-12-14 | — | — | EP | disclosed |
| EP-0623675-A1 | Altered affinity polypeptides of metal chelate binding antibodies | HYBRITECH INCORPORATED (US) | 1994-11-09 | — | — | EP | disclosed |
| EP-0327365-B1 | Improvements in or relating to modified haptens useful as imaging and therapeutic agents | HYBRITECH INC (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0596011-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002652-A2 | MODIFIED HAPTENS USEFUL AS IMAGING AND THERAPEUTIC AGENTS | HYBRITECH INCORPORATED (US) | 1993-02-18 | — | — | WO | disclosed |
| WO-1993002105-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1993-02-04 | — | — | WO | disclosed |
| EP-0217577-B1 | ANTIBODY COMPLEXES OF HAPTEN-MODIFIED DIAGNOSTIC OR THERAPEUTIC AGENTS | HYBRITECH INCORPORATED (US) | 1992-06-10 | — | — | EP | disclosed |
| US-5112951-A | Elution from sulfonated solid support | HYBRITECH INCORPORATED (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0415557-A2 | Separation of anti-metal chelate antibodies | HYBRITECH INCORPORATED (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0369566-A2 | Bifunctional chimeric antibodies | HYBRITECH INCORPORATED (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0369567-A2 | Chimeric antibodies directed against metal chelates | HYBRITECH INCORPORATED (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0327365-A2 | Improvements in or relating to modified haptens useful as imaging and therapeutic agents | HYBRITECH INCORPORATED (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0217577-A2 | Antibody complexes of hapten-modified diagnostic or therapeutic agents | HYBRITECH INCORPORATED (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4622420-A | Chelating agents and method | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-11-11 | — | — | US | disclosed |