Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 6/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9346268 | 0.99 | PTK2 (0.38) | HTR1AHTR2ADRD2SMN1; SMN2DRD1 | |
| SCHEMBL9345625 | 0.97 | PTK2 (0.36) | HTR1AHTR2ADRD2SMN1; SMN2DRD1 | |
| SCHEMBL9349805 | 0.88 | SMN1; SMN2 (0.41) | HTR1AHTR2ADRD2SMN1; SMN2DRD3 | |
| SCHEMBL9345574 | 0.86 | FTO (0.40) | HTR1AHTR2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9344898 | 0.85 | TSHR (0.46) | HTR1AHTR2ADRD2DRD1DRD5 | |
| SCHEMBL9349897 | 0.85 | SMN1; SMN2 (0.39) | HTR1AHTR2ADRD2SMN1; SMN2DRD3 | |
| SCHEMBL9344868 | 0.85 | MAPT (0.41) | HTR1AHTR2ASMN1; SMN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL9346272 | 0.84 | TSHR (0.46) | HTR1AHTR2ADRD2DRD1DRD5 | |
| SCHEMBL9345630 | 0.83 | TSHR (0.48) | HTR1AHTR2ADRD2KDM4EALDH1A1 | |
| SCHEMBL9349852 | 0.82 | FTO (0.41) | SMN1; SMN2LMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5001037-A | — | — | None | — | — | JP | disclosed |
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |
| JP-H051037-A | SUBSTITUTED SULFONAMIDE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME DERIVATIVE | ASAHI CHEM IND CO LTD | 1993-01-08 | — | — | JP | disclosed |