Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 10/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9346272 | 0.99 | TSHR (0.46) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9345630 | 0.97 | TSHR (0.48) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9349813 | 0.87 | TSHR (0.48) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9344897 | 0.85 | HTR1A (0.38) | HTR7HTR6HTR1AHTR2AALDH1A1 | |
| SCHEMBL9345579 | 0.85 | TSHR (0.51) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9349900 | 0.85 | TSHR (0.50) | TSHRALOX15HTR7HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL9346268 | 0.85 | PTK2 (0.38) | HTR7HTR6HTR1AHTR2AALDH1A1 | |
| SCHEMBL9349856 | 0.83 | HTR7 (0.49) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9344872 | 0.83 | TSHR (0.53) | TSHRALOX15HTR7HTR6HTR1A | |
| SCHEMBL9345625 | 0.83 | PTK2 (0.36) | TSHRALOX15HTR7HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5001037-A | — | — | None | — | — | JP | disclosed |
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |
| JP-H051037-A | SUBSTITUTED SULFONAMIDE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME DERIVATIVE | ASAHI CHEM IND CO LTD | 1993-01-08 | — | — | JP | disclosed |