Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345574 | 0.90 | FTO (0.40) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9349852 | 0.89 | FTO (0.41) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9398477 | 0.89 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9349805 | 0.86 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9398291 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9346883 | 0.85 | SIGMAR1 (0.39) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9344897 | 0.85 | HTR1A (0.38) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9349788 | 0.85 | MAPT (0.40) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9346268 | 0.84 | PTK2 (0.38) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL9344872 | 0.84 | TSHR (0.53) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |