Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657088 | 0.80 | ACHE (0.55) | ALDH1A1KMT2AMAPK1HTTMAPT | |
| SCHEMBL30920094 | 0.77 | ACHE (0.58) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7810311 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2AMAPK1TP53POLB | |
| SCHEMBL10759527 | 0.76 | ACHE (0.57) | DRD2DRD4DRD3 | |
| SCHEMBL7651915 | 0.74 | ACHE (0.62) | HTTPKMDRD2DRD4DRD3 | |
| SCHEMBL19770184 | 0.74 | ACHE (0.62) | HTTPKMDRD2DRD4DRD3 | |
| SCHEMBL8782383 | 0.74 | ALDH1A1 (0.65) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7952371 | 0.74 | ACHE (0.66) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL7852368 | 0.72 | ACHE (0.64) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL9216116 | 0.72 | ACHE (0.58) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364864-A | Enzyme inhibitors | PIERRE FABRE MEDICAMENT (FR) | 1994-11-15 | — | — | US | disclosed |