Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782381 | 0.92 | — | — | |
| SCHEMBL8782059 | 0.89 | BCL6 (0.60) | — | |
| SCHEMBL8782371 | 0.89 | CHRM4 (0.64) | ALDH1A1 | |
| SCHEMBL8783146 | 0.88 | CHRM4 (0.64) | — | |
| SCHEMBL8782053 | 0.87 | UBE2M (0.62) | KMT2A | |
| SCHEMBL8782456 | 0.86 | ACHE (0.58) | — | |
| SCHEMBL9344014 | 0.85 | ACHE (0.62) | — | |
| SCHEMBL8782423 | 0.85 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL8782388 | 0.85 | ALDH1A1 (0.69) | ALDH1A1 | |
| SCHEMBL8782166 | 0.85 | THRB (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516520-B1 | 1,4-Disubstituted piperidines, their preparation and therapeutical application | PF MEDICAMENT (FR) | 1997-01-02 | — | — | EP | claimed |
| US-5364864-A | Enzyme inhibitors | PIERRE FABRE MEDICAMENT (FR) | 1994-11-15 | — | — | US | claimed |
| US-5364864-A | Enzyme inhibitors | PIERRE FABRE MEDICAMENT (FR) | 1994-11-15 | — | — | US | disclosed |