Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647718 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL3018392 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL1603802 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22647791 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22607980 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL521587 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL919347 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL6562247 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22647724 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL27640559 | 0.98 | TSHR (0.68) | TSHRNAAAEPHX1RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223894-A1 | OPIOID RECEPTOR ANTAGONIST PRODRUGS | NIRSUM LABORATORIES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| US-5290325-A | Compounds such as methyl pyruvate to lower air pollution | UNION OIL COMPANY OF CALIFORNIA (US) | 1994-03-01 | — | — | US | disclosed |