SCHEMBL521587

SCHEMBL521587

CCCCCCCOC(=O)C(C)=O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
NAAA Q02083 1/20 0.59
EPHX1 P07099 1/20 0.55
RAD52 P43351 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
ALDH1A1 P00352 2/20 0.54
CES2 O00748 1/20 0.52
HCAR2 Q8TDS4 1/20 0.50
FAAH O00519 1/20 0.48
LMNA P02545 1/20 0.48
ACHE P22303 6/20 0.48
DGKA P23743 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9345377 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647718 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3018392 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL1603802 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647791 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22607980 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL919347 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL6562247 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647724 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL27640559 0.98 TSHR (0.68) TSHRNAAAEPHX1RAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100216749-A1 Combination Therapy for Neuroprotection S.H. PHARMA., LTD (KR) 2010-08-26 US claimed
WO-2009045083-A2 COMBINATION THERAPY FOR NEUROPROTECTION S.H. PHARMA., LTD (KR) 2009-04-09 WO claimed
CN-119730951-A Method for producing microparticles 巴斯夫欧洲公司 2025-03-28 CN disclosed
CN-114096234-A Method for producing microparticles loaded with volatile organic active 巴斯夫欧洲公司 2022-02-25 CN disclosed
US-20210393558-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF PRESSURE ULCERS TECHNION RES & DEVELOPMENT FOUND LTD (IL) 2021-12-23 US disclosed
CN-113164897-A Method for preparing microparticles filled with active material 巴斯夫欧洲公司 2021-07-23 CN disclosed
EP-3731838-A2 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF PRESSURE ULCERS Technion - Research & Development Foundation Ltd (IL) 2020-11-04 EP disclosed
EP-1874407-B1 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG ENTWICKLUNG UND DIAGNOSTIK GMB (DE) 2015-09-09 EP disclosed
CN-102365255-B Method for producing alcohol compound and catalyst therefor SUMITOMO CHEMICAL CO 2015-01-07 CN disclosed
CN-102365254-B Method for producing alcohol compound SUMITOMO CHEMICAL CO 2014-08-27 CN disclosed
EP-1877141-B1 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST BACTERIA BIOMAC PRIVATINSTITUT FUER MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG ENTWICKLUNG UND DIAGNOSTIK GM (DE) 2013-06-12 EP disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
EP-2415741-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
US-20120010417-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-20100216749-A1 Combination Therapy for Neuroprotection S.H. PHARMA., LTD (KR) 2010-08-26 US disclosed
US-20100204161-A1 Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use Against Bacteria BIOMAC PRIVATINSTITUT FUR MEDIZINISHE UND ZAHMEDIZ FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2010-08-12 US disclosed
WO-2009045083-A2 COMBINATION THERAPY FOR NEUROPROTECTION S.H. PHARMA., LTD (KR) 2009-04-09 WO disclosed
US-20080300303-A1 Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use As Anti-Fungal Agents BIOMAC PRIVATINSTITUT FUER MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2008-12-04 US disclosed
US-4006132-A 1'-Formyl-1'-halobenzeneazomethane compounds having herbicidal activity THE UPJOHN COMPANY (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300303-A1 Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use As Anti-Fungal Agents GLO1, G6PD, GRHPR TSHR 4035/4885NAAA 1464/4885EPHX1 372/4885
US-20120010417-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND ADH1A, ADH1C, ADH5 TSHR 2221/4885NAAA 155/4885EPHX1 3615/4885
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR ADH1A, ADH1C, ADH5 TSHR 2411/4885NAAA 834/4885EPHX1 1905/4885
US-20100204161-A1 Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use Against Bacteria GLO1, G6PD, GRHPR TSHR 2605/4885NAAA 1316/4885EPHX1 220/4885
US-20100216749-A1 Combination Therapy for Neuroprotection MPO, BDNF, NLN TSHR 4770/4885NAAA 1869/4885EPHX1 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.