SCHEMBL1603802

SCHEMBL1603802

CCCCCCCCOC(=O)C(C)=O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
NAAA Q02083 1/20 0.59
EPHX1 P07099 1/20 0.55
RAD52 P43351 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
ALDH1A1 P00352 2/20 0.54
CES2 O00748 1/20 0.52
HCAR2 Q8TDS4 1/20 0.50
FAAH O00519 1/20 0.48
LMNA P02545 1/20 0.48
ACHE P22303 6/20 0.48
DGKA P23743 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9345377 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647718 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL3018392 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647791 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22607980 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL521587 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL919347 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL6562247 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL22647724 1.00 TSHR (0.70) TSHRNAAAEPHX1RAD52NPSR1
SCHEMBL27640559 0.98 TSHR (0.68) TSHRNAAAEPHX1RAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100216749-A1 Combination Therapy for Neuroprotection S.H. PHARMA., LTD (KR) 2010-08-26 US claimed
WO-2009045083-A2 COMBINATION THERAPY FOR NEUROPROTECTION S.H. PHARMA., LTD (KR) 2009-04-09 WO claimed
US-20260076935-A1 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2026-03-19 US disclosed
EP-4683625-A2 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE The Trustees Of Columbia University In The City Of New York (US) 2026-01-28 EP disclosed
WO-2025058667-A2 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-03-20 WO disclosed
EP-4329743-A1 PYRUVATE ESTERS FOR THE TREATMENT OF VIRAL DISEASES Birkenmeier, Gerd (DE) 2024-03-06 EP disclosed
US-20230044979-A1 ANIMAL CELL CULTURING METHOD AJINOMOTO CO., INC. (JP) 2023-02-09 US disclosed
EP-4123013-A1 ANIMAL CELL CULTURING METHOD AJINOMOTO CO., INC. (JP) 2023-01-25 EP disclosed
WO-2022228652-A1 MEANS AND METHOD FOR TREATING VIRAL INFECTIONS BIRKENMEIER GERD (DE) 2022-11-03 WO disclosed
WO-2022228651-A1 PYRUVATE ESTERS FOR THE TREATMENT OF VIRAL DISEASES BIRKENMEIER GERD (DE) 2022-11-03 WO disclosed
CN-115279893-A Method for culturing animal cells 味之素株式会社 2022-11-01 CN disclosed
EP-1877141-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST BACTERIA Biomac Privatinstitut für medizinische und Zahnmedizinische Forschung, Entwicklung und Diagnostik GmbH (DE) 2008-01-16 EP disclosed
EP-1874407-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS Biomac Privatinstitut für medizinische und Zahnmedizinische Forschung, Entwicklung und Diagnostik GmbH (DE) 2008-01-09 EP disclosed
US-7230062-B2 Acrylic copolymer KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2007-06-12 US disclosed
WO-2006108681-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST BACTERIA BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2006-10-19 WO disclosed
WO-2006108682-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2006-10-19 WO disclosed
WO-2006108680-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST PROTOZOA AND HELMINTHES BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2006-10-19 WO disclosed
WO-2006108679-A2 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE TO COMBAT CANCER BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH (DE) 2006-10-19 WO disclosed
US-20050182224-A1 Acrylic copolymer KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2005-08-18 US disclosed
US-4006132-A 1'-Formyl-1'-halobenzeneazomethane compounds having herbicidal activity THE UPJOHN COMPANY (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076935-A1 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE PC, PDK1, PDK4 TSHR 2677/4885NAAA 4242/4885EPHX1 151/4885
US-20230044979-A1 ANIMAL CELL CULTURING METHOD NPEPPS, ZDHHC2, EIF2A TSHR 1782/4885NAAA 2205/4885EPHX1 2323/4885
US-20100216749-A1 Combination Therapy for Neuroprotection MPO, BDNF, NLN TSHR 4770/4885NAAA 1869/4885EPHX1 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.