Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345377 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22647718 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL3018392 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL1603802 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22647791 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22607980 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL521587 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL6562247 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL22647724 | 1.00 | TSHR (0.70) | TSHRNAAAEPHX1RAD52NPSR1 | |
| SCHEMBL27640559 | 0.98 | TSHR (0.68) | TSHRNAAAEPHX1RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101883773-B | Polyketal compounds, synthesis, and applications | SEGETIS INC | 2014-05-21 | — | — | CN | disclosed |
| US-8546519-B2 | Polyketal compounds, synthesis, and applications | SEGETIS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | SEGETIS, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| CN-101883773-A | Polyketal compounds, synthesis, and applications | SEGETIS INC | 2010-11-10 | — | — | CN | disclosed |
| EP-2205606-A2 | POLYKETAL COMPOUNDS, SYNTHESIS, AND APPLICATIONS | Segetis, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009049041-A2 | POLYKETAL COMPOUNDS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| US-7230062-B2 | Acrylic copolymer | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20050182224-A1 | Acrylic copolymer | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | TKT, KYAT1, KHK | TSHR 3422/4885NAAA 530/4885EPHX1 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.