Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CCR5 | P51681 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346531 | 0.83 | LMNA (0.51) | MMP2ANPEPALDH1A1CCR5LMNA | |
| SCHEMBL10508472 | 0.79 | ACE (0.62) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL10508467 | 0.79 | ACE (0.62) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL9814479 | 0.76 | ACE (0.58) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL178991 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CCR5SMN1; SMN2GAA | |
| SCHEMBL8828176 | 0.73 | KDM4E (0.55) | MMP2ANPEPALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11494753 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL15458921 | 0.73 | ITGB1 (0.41) | ALDH1A1CCR5 | |
| SCHEMBL10508327 | 0.73 | ACE (0.60) | RAB9AL3MBTL1MAPK1ACEFKBP1A | |
| SCHEMBL10508329 | 0.73 | ACE (0.60) | RAB9AL3MBTL1MAPK1ACEFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333522-B1 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5232923-A | Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0333522-A2 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-20 | — | — | EP | disclosed |