Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.63 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | HTR1B | P28222 | 2/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033807 | 0.87 | HTR1A (0.80) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL19091219 | 0.83 | RAB9A (0.79) | HTR1ADRD2HTR2AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL27860615 | 0.82 | HTR1A (0.73) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL492205 | 0.80 | HRH3 (0.84) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL9349929 | 0.79 | SIGMAR1 (0.69) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL9349920 | 0.79 | SIGMAR1 (0.69) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL22266171 | 0.79 | NPC1 (0.72) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL2823877 | 0.78 | HRH3 (0.87) | HRH1HRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4084100 | 0.78 | HRH3 (0.87) | HRH1HRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19080586 | 0.78 | HTR1A (0.63) | HTR1ADRD2HTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |