SCHEMBL934570

SCHEMBL934570

CCO[Si](CCC(N)N1CCNCC1)(OCC)OCC

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
CACNA1F O60840 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CACNA1D Q01668 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30
CACNA1S Q13698 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9420797 0.91
SCHEMBL28372506 0.88
SCHEMBL935538 0.85 SLC6A2 (0.32) SLC6A2SLC6A4CYP2D6SLC6A3KCNH2
SCHEMBL935172 0.80 KMT2A (0.37)
SCHEMBL2116575 0.76 SIGMAR1 (0.36) SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL4061260 0.75 POLB (0.38) CYP3A4CYP2D6
SCHEMBL9420765 0.74 CYP2D6 (0.30) SLC6A2SLC6A4CYP2D6SLC6A3KCNH2
SCHEMBL9420793 0.74 SMN1; SMN2 (0.33)
SCHEMBL9420798 0.73
SCHEMBL542927 0.73 SIGMAR1 (0.43) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
EP-2454326-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS Wacker Chemie AG (DE) 2012-05-23 EP disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed
WO-2011006808-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2011-01-20 WO disclosed