Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935538 | 0.89 | SLC6A2 (0.32) | CYP2D6SLC6A2SLC6A4HTR7SLC6A3 | |
| SCHEMBL9420785 | 0.86 | — | — | |
| SCHEMBL9420797 | 0.85 | — | — | |
| SCHEMBL7023231 | 0.76 | GNAO1 (0.41) | CYP2D6 | |
| SCHEMBL5474453 | 0.76 | LMNA (0.33) | SLC6A2SLC6A4 | |
| SCHEMBL10705422 | 0.75 | GNAO1 (0.43) | CYP2D6 | |
| SCHEMBL10706538 | 0.75 | GNAO1 (0.43) | CYP2D6 | |
| SCHEMBL8502189 | 0.75 | GNAO1 (0.43) | CYP2D6 | |
| SCHEMBL27826968 | 0.75 | GNAO1 (0.43) | CYP2D6 | |
| SCHEMBL542927 | 0.74 | SIGMAR1 (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355426-B1 | Fast-curve polyurethane sealant composition containing silylsubstituted piperazine accelerators | ADCO PRODUCTS INC (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0355426-A2 | Fast-curve polyurethane sealant composition containing silylsubstituted piperazine accelerators | ADCO PRODUCTS, INC. (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0355426-B1 | Fast-curve polyurethane sealant composition containing silylsubstituted piperazine accelerators | ADCO PRODUCTS INC (US) | 1994-02-16 | — | — | EP | disclosed |
| EP-0355426-A2 | Fast-curve polyurethane sealant composition containing silylsubstituted piperazine accelerators | ADCO PRODUCTS, INC. (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4894426-A | Fast-cure polyurethane sealant composition containing silyl-substituted piperazine accelerators | BASF CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |