Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372506 | 0.88 | — | — | |
| SCHEMBL3712868 | 0.85 | KMT2A (0.37) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL934570 | 0.80 | SLC6A2 (0.30) | — | |
| SCHEMBL28213937 | 0.77 | KMT2A (0.35) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8557598 | 0.76 | KMT2A (0.37) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL936325 | 0.75 | KMT2A (0.38) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30349741 | 0.73 | KCNH2 (0.39) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16714792 | 0.72 | KMT2A (0.39) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9420797 | 0.72 | — | — | |
| SCHEMBL181625 | 0.72 | ALDH1A1 (0.39) | KMT2AALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357755-B2 | Cross-linkable organosilicon-based compositions | WACKER CHEMIE AG (DE) | 2013-01-22 | — | — | US | disclosed |
| EP-2454326-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | Wacker Chemie AG (DE) | 2012-05-23 | — | — | EP | disclosed |
| US-20120123048-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2011006808-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2011-01-20 | — | — | WO | disclosed |