Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423839 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL29098552 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL28233117 | 0.86 | LMNA (0.53) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL27572690 | 0.85 | LMNA (0.62) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL5973498 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL9781701 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL2423254 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL19846185 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL19837280 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 | |
| SCHEMBL19837282 | 0.83 | LMNA (0.66) | ALDH1A1LMNAMAPK1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539460-B1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B | RHONE POULENC RORER SA (FR) | 1994-10-05 | — | — | EP | claimed |
| US-5326782-A | Salts derived from 26-(dialkylaminoalkylsulphonyl)pristinamycin IIB | RHONE-POULENC RORER S.A. (FR) | 1994-07-05 | — | — | US | claimed |
| EP-0539460-A1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B. | RHONE POULENC RORER SA (FR) | 1993-05-05 | — | — | EP | claimed |
| WO-1992001694-A1 | NEW SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II¿B? | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | claimed |
| US-7262221-B2 | Amphiphilic star-like macromolecules for drug delivery | RUTGERS THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-08-28 | — | — | US | disclosed |
| EP-0539460-B1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B | RHONE POULENC RORER SA (FR) | 1994-10-05 | — | — | EP | disclosed |
| US-5326782-A | Salts derived from 26-(dialkylaminoalkylsulphonyl)pristinamycin IIB | RHONE-POULENC RORER S.A. (FR) | 1994-07-05 | — | — | US | disclosed |
| EP-0539460-A1 | SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B. | RHONE POULENC RORER SA (FR) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001694-A1 | NEW SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II¿B? | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |
| WO-1992001694-A1 | NEW SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II¿B? | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |