Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346597 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL1168152 | 0.87 | MMP1 (0.42) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL20590957 | 0.87 | LMNA (0.55) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL6829086 | 0.85 | LMNA (0.58) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL27664735 | 0.84 | LMNA (0.56) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL1468445 | 0.83 | MMP1 (0.44) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL14935874 | 0.83 | LMNA (0.39) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL3749627 | 0.83 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL14423839 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL94758 | 0.82 | MMP1 (0.38) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118765198-A | Methods and compositions for treating parkinson's disease | 纽罗德姆有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-116964069-A | Stabilized liquid compositions comprising levodopa-tyrosine conjugates and uses thereof | 纽罗德姆有限公司 | 2023-10-27 | — | — | CN | disclosed |