SCHEMBL934670

SCHEMBL934670

Cc1ccc2nc(O)cc(C)c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
GAA P10253 3/20 0.49
HTT P42858 1/20 0.49
ELANE P08246 1/20 0.49
LMNA P02545 5/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
RAD52 P43351 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 2/20 0.43
KDM4E B2RXH2 6/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ACHE P22303 4/20 0.42
BCHE P06276 3/20 0.42
GRIN1 Q05586 3/20 0.42
GRIN2A Q12879 3/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845288 1.00 KMT2A (0.56) KMT2AMEN1GAAHTTELANE
SCHEMBL11401003 0.84 ELANE (0.49) KMT2AMEN1GAAELANELMNA
SCHEMBL15472861 0.84 KDM4E (0.57) KMT2AMEN1GAARAD52POLB
SCHEMBL5349570 0.81 TSHR (0.44) KMT2AMEN1GAAHTTLMNA
SCHEMBL19689622 0.81 LMNA (0.68) KMT2AMEN1ELANELMNAL3MBTL1
SCHEMBL3531515 0.79 LMNA (0.66) KMT2AMEN1GAAHTTELANE
SCHEMBL17479061 0.78 MEN1 (0.43) KMT2AMEN1LMNAL3MBTL1KDM4E
SCHEMBL19689623 0.78 ESR1 (0.49) KMT2AMEN1GAAHTTELANE
SCHEMBL20851772 0.78 ALDH1A1 (0.55) KMT2AMEN1GAAELANELMNA
SCHEMBL2655065 0.78 ALDH1A1 (0.63) KMT2AMEN1ELANELMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666852-B1 ETCHING SOLUTION HAVING SILICON OXIDE CORROSION INHIBITOR AND METHOD OF USING THE SAME VERSUM MAT US LLC (US) 2022-01-05 EP claimed
EP-2453927-B1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES UNIV DENMARK TECH DTU (DK) 2019-05-15 EP claimed
US-8920775-B2 Loading technique for preparing radionuclide containing nanoparticles TECHNICAL UNIVERSITY OF DENMARK (DK) 2014-12-30 US claimed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US claimed
EP-2453927-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES Technical University of Denmark (DK) 2012-05-23 EP claimed
WO-2011006510-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES TECHNICAL UNIVERSITY OF DENMARK (DK) 2011-01-20 WO claimed
US-20240148918-A1 Loading of Alginate Microspheres BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-05-09 US disclosed
EP-4301341-A1 LOADING OF ALGINATE MICROSPHERES Board of Regents, The University of Texas System (US) 2024-01-10 EP disclosed
CN-117241781-A Loading of alginate microspheres 德克萨斯大学系统董事会 2023-12-15 CN disclosed
WO-2021116712-A1 FUNCTIONALISED MICROBUBBLE MEDIATED CELL TAGGING OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-06-17 WO disclosed
EP-2453927-B1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES UNIV DENMARK TECH DTU (DK) 2019-05-15 EP disclosed
EP-2651447-B1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS UNIV DENMARK TECH DTU (DK) 2018-08-29 EP disclosed
US-20160158392-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2016-06-09 US disclosed
US-8920775-B2 Loading technique for preparing radionuclide containing nanoparticles TECHNICAL UNIVERSITY OF DENMARK (DK) 2014-12-30 US disclosed
EP-2651447-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS Technical University of Denmark (DK) 2013-10-23 EP disclosed
US-20130251630-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2013-09-26 US disclosed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US disclosed
WO-2012079582-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS TECHNICAL UNIVERSITY OF DENMARK (DK) 2012-06-21 WO disclosed
EP-2453927-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES Technical University of Denmark (DK) 2012-05-23 EP disclosed
WO-2011006510-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES TECHNICAL UNIVERSITY OF DENMARK (DK) 2011-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES LIPG, NPC1L1, CD47 KMT2A 3475/4885MEN1 154/4885GAA 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.