Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223314 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1MAPTGAAGFER | |
| SCHEMBL4029580 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL3806183 | 0.76 | PTGDR2 (0.56) | TSHRALDH1A1KMT2ANPSR1POLB | |
| SCHEMBL14468465 | 0.73 | ALDH1A1 (0.56) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL24405304 | 0.72 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL10288373 | 0.72 | IRAK4 (0.47) | TSHRALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL1128732 | 0.71 | TSHR (0.66) | TSHRALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL3521281 | 0.71 | TSHR (0.66) | TSHRTDP1CYP3A4MEN1KMT2A | |
| SCHEMBL629596 | 0.71 | CYP19A1 (0.46) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL23174608 | 0.70 | HTR2A (0.51) | TSHRALDH1A1TDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603339-A1 | POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES | AMOCO CORPORATION (US) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993006151-A1 | POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES | AMOCO CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |