Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348802 | 0.84 | MAPT (0.53) | GAAPOLBMAPTALDH1A1TDP1 | |
| SCHEMBL9348893 | 0.80 | DHFR (0.43) | GAAPOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9347887 | 0.79 | SRD5A2 (0.40) | GAAPOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8074321 | 0.78 | ALDH1A1 (0.54) | POLBL3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL10401189 | 0.78 | NPC1 (0.42) | L3MBTL1ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL10401177 | 0.77 | GAA (0.54) | GAAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL9033779 | 0.76 | GAA (0.49) | GAAL3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL7372599 | 0.75 | GAA (0.55) | GAAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL11798494 | 0.74 | TP53 (0.48) | GAAPOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8159189 | 0.73 | GAA (0.58) | GAAPOLBL3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294035-B1 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-4935240-A | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0294035-A2 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-07 | — | — | EP | disclosed |