Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040384 | 0.85 | EIF4E (0.46) | EIF4EKMOCNR1MCL1HSD17B14 | |
| SCHEMBL1050097 | 0.82 | EIF4E (0.44) | EIF4EKMOCNR1MCL1HSD17B14 | |
| SCHEMBL4037851 | 0.78 | PTGER1 (0.47) | EIF4EMCL1PTGER1DHODH | |
| SCHEMBL912838 | 0.75 | KDM4E (0.45) | EIF4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL951541 | 0.74 | HSD17B14 (0.43) | EIF4EALDH1A1KMOMCL1HSD17B14 | |
| SCHEMBL545109 | 0.73 | HSD17B14 (0.40) | EIF4EALDH1A1LMNACNR1MCL1 | |
| Hydrochloric Acid SCHEMBL544567 | 0.73 | KDM4E (0.41) | EIF4EKMOMCL1 | |
| SCHEMBL934656 | 0.72 | CTSA (0.44) | — | |
| SCHEMBL4041123 | 0.70 | MCL1 (0.46) | CNR1MCL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL544584 | 0.70 | NOTUM (0.51) | CNR1MCL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011007091-A1 | DERIVATIVES OF 5,6-BISARYL-2-PYRIDINE-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF AS UROTENSIN-II RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2011-01-20 | — | — | WO | disclosed |