Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502990 | 0.97 | ALOX5 (0.55) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL9351914 | 0.93 | ALOX5 (0.47) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL5615700 | 0.93 | GABRA1 (0.53) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL27745672 | 0.93 | GABRA1 (0.53) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL9351889 | 0.90 | GABRA1 (0.57) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL4959229 | 0.88 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL11618297 | 0.88 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL11615237 | 0.88 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL4960231 | 0.88 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL11621072 | 0.88 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258598-B1 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | GOODRICH CO B F (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0253010-B1 | N-(SUBSTITUTED CYCLIC ALKYLENEIMINE)-ALPHA-(3,5-DI-ALKYL-4-HYDROXY-PHENYL)-ALPHA, ALPHA-DIALKYL ACETAMIDES | The B.F. GOODRICH Company (US) | 1992-12-02 | — | — | EP | disclosed |
| US-5096949-A | Heat and oxidation resistance, photostability; polyolefins; uv rad | THE B. F. GOODRICH COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4920228-A | N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith | THE B. F. GOODRICH COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| US-4780495-A | HEAT, OXIDATION, AND LIGHT STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0284800-A1 | N-(substituted piperidinyl)-alpha-(3,5-dialkyl-4-hydroxyphenyl)-alpha', alpha''-dialkyl acetamides | THE B.F. GOODRICH COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0141419-B1 | 3,5-DIALKYL-4-HYDROXYPHENYL-SUBSTITUTED DERIVATIVES | The B.F. GOODRICH Company (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258598-A2 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | THE B.F. GOODRICH COMPANY (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0253010-A1 | N-(substituted cyclic alkyleneimine)-alpha-(3,5-di-alkyl-4-hydroxy-phenyl)-alpha, alpha-dialkyl acetamides | The B.F. GOODRICH Company (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4523032-A | 3,5-Dialkyl-4-hydroxyphenyl-substituted acetic acids | THE B. F. GOODRICH COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0141419-A1 | 3,5-Dialkyl-4-hydroxyphenyl-substituted derivatives | The B.F. GOODRICH Company (US) | 1985-05-15 | — | — | EP | disclosed |