Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849891 | 0.86 | AKR1C1 (0.47) | LMNACA2CA1ALDH1A1TDP1 | |
| SCHEMBL10703712 | 0.86 | AKR1C1 (0.47) | LMNACA2CA1ALDH1A1TDP1 | |
| SCHEMBL8579286 | 0.82 | CA2 (0.41) | LMNACA2CA1ALDH1A1TDP1 | |
| SCHEMBL10701913 | 0.78 | ACHE (0.45) | CA2CA1ALDH1A1TDP1GAA | |
| SCHEMBL5573143 | 0.77 | CA2 (0.45) | CA2CA1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL297823 | 0.76 | ACHE (0.58) | LMNACA2CA1ALDH1A1TDP1 | |
| Bicarbonate SCHEMBL11054659 | 0.76 | GLRA3 (0.43) | LMNACA2CA1ALDH1A1TDP1 | |
| SCHEMBL5667067 | 0.75 | LMNA (0.46) | LMNA | |
| SCHEMBL8850252 | 0.73 | CNR1 (0.39) | LMNACA2CA1ALDH1A1TDP1 | |
| Cyclohexane SCHEMBL5068614 | 0.71 | CA2 (0.47) | LMNACA2CA1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258598-B1 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | GOODRICH CO B F (US) | 1994-09-07 | — | — | EP | claimed |