SCHEMBL9348261

SCHEMBL9348261

COc1ccccc1OCC(C)Oc1ccccc1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
CYP1A2 P05177 2/20 0.56
AGTR1 P30556 1/20 0.56
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
KDM4E B2RXH2 1/20 0.49
KMT2A Q03164 1/20 0.49
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348551 0.86 MTNR1A (0.48) LMNACYP1A2AGTR1MTNR1AMTNR1B
SCHEMBL1446334 0.82 LMNA (0.61) LMNACYP1A2AGTR1CA12CA1
SCHEMBL7412875 0.78 MTNR1A (0.54) LMNACYP1A2AGTR1MTNR1AMTNR1B
SCHEMBL10639362 0.78 LMNA (0.58) LMNACYP1A2AGTR1CA12CA1
SCHEMBL8684485 0.78 LMNA (0.58) LMNACYP1A2AGTR1CA12CA1
SCHEMBL4315148 0.78 LMNA (0.43) LMNACYP1A2AGTR1MTNR1AMTNR1B
SCHEMBL11024920 0.78 MTNR1A (0.54) LMNACYP1A2AGTR1MTNR1AMTNR1B
SCHEMBL7415697 0.78 LMNA (0.58) LMNACYP1A2AGTR1CA12CA1
SCHEMBL1496733 0.78 LMNA (0.68) LMNACYP1A2AGTR1CA12CA1
SCHEMBL29120476 0.78 LMNA (0.58) LMNACYP1A2AGTR1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2070481-A None JP disclosed
EP-0357409-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
US-4994431-A Containing colorless dye precursor, color developer and 1-alkoxy-phenoxy-2-aryloxypropane sensitizer; preservation stability, high sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed
JP-H0270481-A THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1990-03-09 JP disclosed
EP-0357409-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed