Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565341 | 0.88 | TDP1 (0.42) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL7051684 | 0.85 | ALDH1A1 (0.46) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL4195640 | 0.84 | CYP1B1 (0.57) | TDP1LMNAALDH1A1GAAKDM4E | |
| SCHEMBL11389346 | 0.82 | ASAH1 (0.44) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL5161779 | 0.80 | ASAH1 (0.47) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL11408791 | 0.80 | ALDH1A1 (0.47) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL5490233 | 0.79 | TDP1 (0.52) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL6364898 | 0.79 | TDP1 (0.52) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL10384427 | 0.79 | ASAH1 (0.49) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL9831331 | 0.79 | ASAH1 (0.49) | TDP1LMNAALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920065-B | Benzil compound and preparation method and application thereof | 上海中医药大学 | 2023-04-25 | — | — | CN | disclosed |
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |