Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348267 | 0.88 | TDP1 (0.49) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL7051684 | 0.74 | ALDH1A1 (0.46) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL4195640 | 0.73 | CYP1B1 (0.57) | TDP1LMNAALDH1A1GAAKDM4E | |
| SCHEMBL6364898 | 0.72 | TDP1 (0.52) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL5490233 | 0.72 | TDP1 (0.52) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL11389346 | 0.71 | ASAH1 (0.44) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL6666103 | 0.71 | TDP1 (0.50) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL19615470 | 0.71 | TDP1 (0.50) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL6127956 | 0.71 | TDP1 (0.65) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL29459229 | 0.71 | TDP1 (0.65) | TDP1LMNAALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531719-A1 | Electrophotographic toners and 3-iminoisoindoline derivatives | BAYER AG (DE) | 1993-03-17 | — | — | EP | disclosed |