Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339539 | 0.76 | TSHR (0.36) | CES2CES1TSHRHPGDALDH1A1 | |
| SCHEMBL6934795 | 0.75 | CES2 (0.41) | CES2CES1TSHRCA1CA2 | |
| SCHEMBL2819121 | 0.74 | TSHR (0.39) | CES1TSHRHPGDALDH1A1CA1 | |
| SCHEMBL10494265 | 0.74 | TSHR (0.39) | CES2TSHRCA1CA2CA9 | |
| SCHEMBL7935122 | 0.74 | TSHR (0.34) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL1608819 | 0.74 | CES2 (0.43) | CES2CES1TSHRCA1CA2 | |
| SCHEMBL7937308 | 0.72 | TSHR (0.38) | CES2CES1TSHRHPGDCA1 | |
| SCHEMBL13303172 | 0.72 | CES1 (0.47) | CES2CES1TSHRCA1CA2 | |
| SCHEMBL29258947 | 0.72 | CES1 (0.47) | CES2CES1TSHRCA1CA2 | |
| SCHEMBL10059143 | 0.72 | CES1 (0.47) | CES2CES1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428706-B1 | PERFLUOROVINYL COMPOUNDS | DOW CHEMICAL CO (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5023380-A | Monomer for thermoplastic resin | THE DOW CHEMICAL COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-4423249-A | APROTIC SOLVENT, METAL HYDROCARBOXIDE, HALOFLUOROALKYL COMPOUND, ETHERIFICATION | THE DOW CHEMICAL COMPANY (US) | 1983-12-27 | — | — | US | disclosed |