Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937308 | 0.98 | TSHR (0.38) | TSHRHPGDRECQLGLAMAPK1 | |
| SCHEMBL537821 | 0.93 | TSHR (0.38) | TSHRHPGDALDH1A1 | |
| SCHEMBL10339539 | 0.76 | TSHR (0.36) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL2819121 | 0.74 | TSHR (0.39) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL10494265 | 0.74 | TSHR (0.39) | TSHRCA1CA2CA9MEN1 | |
| SCHEMBL9348390 | 0.74 | CES2 (0.37) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL9679070 | 0.71 | CES1 (0.39) | TSHRHPGDRECQLBLMCA1 | |
| SCHEMBL27381650 | 0.69 | MEN1 (0.39) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL27747219 | 0.69 | MEN1 (0.39) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL12826538 | 0.68 | TSHR (0.39) | TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232376-B1 | BLEND CONTAINING ORGANOSILICON COMPOUND, PEROXIDE, HINDERED AMINE STABILIZER AND ANTIOXIDANTS | NIPPON UNICAR COMPANY LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-0135923-B1 | PRODUCTION OF WATER-CURABLE, SILANE MODIFIED THERMOPLASTIC POLYMERS | UNION CARBIDE CORPORATION (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4767820-A | HYDROLYZABLE, PENDANT SILANE MOIETIES ON HOMO- OR COPOLYMER OF AN OLEFIN OR DIOLEFIN | UNION CARBIDE CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4753993-A | WATER CURABLE ETHYLENE POLYMERS HAVING PENDANT HYDROLZABLE SILANE GROUPS | UNION CARBIDE CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| US-4707520-A | Composition based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts | UNION CARBIDE CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0212630-A2 | Compositions based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts | UNION CARBIDE CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4579913-A | Composition of a relatively stable polymer of an olefinic monomer and an unsaturated silane, and an organo titanate | UNION CARBIDE CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| US-4526930-A | Contains organotitanate for ester exchange | UNION CARBIDE CORPORATION (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0135923-A2 | Production of water-curable, silane modified thermoplastic polymers | UNION CARBIDE CORPORATION (US) | 1985-04-03 | — | — | EP | disclosed |