Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352484 | 0.84 | PTPN1 (0.47) | PTPN1TSHRMAOBCA1CA2 | |
| SCHEMBL9349724 | 0.84 | PTPN1 (0.47) | PTPN1TSHRMAOBCA1CA2 | |
| SCHEMBL9352494 | 0.81 | TSHR (0.44) | TSHRCA1CA2TDP1ALOX5 | |
| SCHEMBL9348507 | 0.78 | PTPN1 (0.45) | PTPN1TDP1L3MBTL1TAS2R14HTR1A | |
| SCHEMBL9349868 | 0.78 | CRHR1 (0.35) | PTPN1CA1CA2ALOX5ALDH1A1 | |
| SCHEMBL12772157 | 0.77 | KMT2A (0.60) | MAOBTDP1ABCB1PPARGALDH1A1 | |
| SCHEMBL4002789 | 0.76 | ALDH1A1 (0.46) | PTPN1CA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL18029929 | 0.75 | LTA4H (0.57) | PTPN1TSHRMAOBCA1CA2 | |
| SCHEMBL9348530 | 0.75 | MAOB (0.50) | TSHRMAOBTDP1L3MBTL1ABCB1 | |
| SCHEMBL5956203 | 0.73 | PTPN1 (0.58) | PTPN1MAOBCA1CA2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | claimed |
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |