SCHEMBL9348461

SCHEMBL9348461

C=CCS(=O)(=O)Nc1ccc2c(c1NS(=O)(=O)CC=C)C(=O)c1ccccc1C2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
MAPK1 P28482 6/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
PKM P14618 2/20 0.39
KDM4E B2RXH2 2/20 0.38
MMP14 P50281 1/20 0.38
L3MBTL1 Q9Y468 4/20 0.38
RAB9A P51151 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
EGFR P00533 1/20 0.38
PABPC1 P11940 1/20 0.38
PGAM1 P18669 4/20 0.38
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
ALDH1A1 P00352 4/20 0.37
NSD2 O96028 2/20 0.37
LMNA P02545 2/20 0.37
CASP3 P42574 2/20 0.37
SENP7 Q9BQF6 2/20 0.37
SENP6 Q9GZR1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348444 0.85 MAPT (0.51) MAPTMAPK1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL9774586 0.80 PARP14 (0.43) MAPTMAPK1SMN1; SMN2PKMKDM4E
SCHEMBL9027405 0.73 KMT2A (0.49) MAPTMAPK1SMN1; SMN2PKMKDM4E
SCHEMBL10761700 0.68 MAPT (0.47) MAPTMAPK1SMN1; SMN2PKMKDM4E
SCHEMBL27513774 0.68 ALDH1A1 (0.51) MAPTMAPK1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL6420978 0.67 PSIP1 (0.39) MAPTMAPK1SMN1; SMN2KDM4EKMT2A
SCHEMBL21624555 0.67 PSIP1 (0.64) MAPTSMN1; SMN2PKMRAB9AALDH1A1
SCHEMBL11136620 0.67 PSIP1 (0.39) MAPTSMN1; SMN2KDM4EL3MBTL1KMT2A
SCHEMBL16301364 0.67 ALDH1A1 (0.45) MAPTSMN1; SMN2PKML3MBTL1RAB9A
SCHEMBL10767796 0.67 MAOA (0.41) MAPTMAPK1SMN1; SMN2PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409638-B1 Anthraquinone dyes having alkylsulfonylamino substituents MINNESOTA MINING & MFG (US) 1994-08-31 EP disclosed
US-5034547-A Colorfastness MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-23 US disclosed
EP-0409638-A1 Anthraquinone dyes having alkylsulfonylamino substituents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-23 EP disclosed