Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058658 | 0.90 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL9392804 | 0.88 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL12978933 | 0.87 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL18314720 | 0.86 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL8690 | 0.81 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL16033288 | 0.81 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL28701077 | 0.81 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL26343381 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL14226424 | 0.81 | RAB9A (0.52) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL3119487 | 0.81 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |