Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.76 |
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959872 | 0.95 | SMN1; SMN2 (0.73) | SMN1; SMN2NAAAMAPTGAANPC1 | |
| SCHEMBL12445445 | 0.90 | SMN1; SMN2 (0.81) | SMN1; SMN2NAAAMAPTGAANPC1 | |
| SCHEMBL16361209 | 0.89 | SMN1; SMN2 (0.84) | SMN1; SMN2NAAAMAPTGAANPC1 | |
| SCHEMBL25970084 | 0.88 | SMN1; SMN2 (0.96) | SMN1; SMN2NAAAGAANPC1RAB9A | |
| SCHEMBL4354408 | 0.88 | NAAA (0.67) | SMN1; SMN2NAAAMAPTGAANPC1 | |
| SCHEMBL20734830 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2NAAAGAANPC1RAB9A | |
| SCHEMBL731383 | 0.85 | SMN1; SMN2 (0.77) | SMN1; SMN2NAAAMAPTGAANPC1 | |
| SCHEMBL30910449 | 0.84 | SMN1; SMN2 (0.87) | SMN1; SMN2NAAANPC1RAB9AHPGD | |
| SCHEMBL15577818 | 0.84 | SMN1; SMN2 (0.87) | SMN1; SMN2NAAANPC1RAB9AHPGD | |
| SCHEMBL8404704 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488032-B1 | PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF | EINSTEIN COLL MED (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2011037610-A1 | PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-03-31 | — | — | WO | disclosed |
| EP-0357409-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 1994-07-20 | — | — | EP | disclosed |
| US-4994431-A | Containing colorless dye precursor, color developer and 1-alkoxy-phenoxy-2-aryloxypropane sensitizer; preservation stability, high sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0357409-A2 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |