SCHEMBL9348695

SCHEMBL9348695

Cc1cc(C2(c3cc(C)c(Oc4ccc(N)cc4)c(C)c3)CCC(C3CCC(C)CC3)CC2)cc(C)c1Oc1ccc(N)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TEAD4 Q15561 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.30
MITF O75030 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30
NLRP1 Q9C000 1/20 0.30
NOD2 Q9HC29 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348687 1.00 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9349932 1.00 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9348458 0.92 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9348988 0.89 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9350132 0.88 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9352388 0.88 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9350138 0.88 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4TDP1MAPT
SCHEMBL9348789 0.87 POLB (0.39) ALDH1A1MAPTPOLBCYP3A4
SCHEMBL9352634 0.87 POLB (0.39) ALDH1A1MAPTPOLBCYP3A4
SCHEMBL9348785 0.87 POLB (0.39) ALDH1A1MAPTPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389092-B1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORP (JP) 1994-09-07 EP disclosed
US-5152918-A Cyclohexyl aromatic polyimides; controlling pretilt angle CHISSO CORPORATION (JP) 1992-10-06 US disclosed