SCHEMBL9348458

SCHEMBL9348458

Cc1cc(C2(c3cc(C)c(Oc4ccc(N)cc4)c(C)c3)CCC(C)CC2)cc(C)c1Oc1ccc(N)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
TEAD4 Q15561 1/20 0.38
MAPT P10636 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MITF O75030 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
NLRP1 Q9C000 1/20 0.33
NOD2 Q9HC29 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348687 0.92 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9348695 0.92 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9349932 0.92 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9350703 0.86 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9245298 0.85 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9348988 0.85 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9348867 0.85 MAPT (0.42) ALDH1A1SMN1; SMN2MAPTPOLBCYP3A4
SCHEMBL9353585 0.84 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9349994 0.83 NFE2L2 (0.35) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9350132 0.82 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389092-B1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORP (JP) 1994-09-07 EP disclosed
EP-0368604-B1 New diamino and dinitro compounds and a process for preparing the diamino compounds CHISSO CORP (JP) 1994-08-31 EP disclosed
US-5152918-A Cyclohexyl aromatic polyimides; controlling pretilt angle CHISSO CORPORATION (JP) 1992-10-06 US disclosed
US-5008456-A Chemical intermediates for polyamides and polyimides CHISSO CORPORATION (JP) 1991-04-16 US disclosed
EP-0389092-A1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORPORATION (JP) 1990-09-26 EP disclosed
EP-0368604-A2 New diamino and dinitro compounds and a process for preparing the diamino compounds CHISSO CORPORATION (JP) 1990-05-16 EP disclosed