Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494205 | 0.96 | HDAC6 (0.44) | NPC1RAB9APAX8JAK2HDAC6 | |
| SCHEMBL9348678 | 0.91 | HDAC6 (0.42) | NPC1RAB9APAX8JAK2HDAC6 | |
| SCHEMBL9350160 | 0.90 | PLK1 (0.47) | NPC1RAB9APAX8JAK2HDAC6 | |
| SCHEMBL9352868 | 0.88 | ALDH1A1 (0.43) | NPC1RAB9APAX8JAK2HDAC6 | |
| SCHEMBL10706373 | 0.86 | HDAC6 (0.44) | NPC1RAB9APAX8JAK2HDAC6 | |
| SCHEMBL7604538 | 0.86 | CYP3A4 (0.49) | RAB9AGPBAR1ALDH1A1TP53CNR2 | |
| SCHEMBL5311189 | 0.81 | CYP3A4 (0.39) | RAB9AGPBAR1ALDH1A1TP53CNR2 | |
| SCHEMBL7607605 | 0.80 | PLK1 (0.47) | NPC1RAB9AHDAC6LMNAALDH1A1 | |
| SCHEMBL9350203 | 0.78 | ALDH1A1 (0.42) | NPC1RAB9AHDAC6GPBAR1ALDH1A1 | |
| SCHEMBL9348811 | 0.78 | TAS1R3 (0.40) | RAB9AJAK2LMNAALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
| US-5245071-A | Insecticides | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-09-14 | — | — | US | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| US-4920135-A | NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-04-24 | — | — | US | disclosed |
| US-4833151-A | INTERFERES WITH METAMORPHOSES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-05-23 | — | — | US | disclosed |
| US-4607044-A | Insecticidal use of ureas and thioureas | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-08-19 | — | — | US | disclosed |
| US-4166124-A | IMIDAZOLE OR PYRIMIDINE RINGS | U.S. PHILIPS CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| US-4013717-A | BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES | U.S. PHILIPS CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3989842-A | Certain substituted benzoyl urea insecticides | U.S. PHILIPS CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |