Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316136 | 0.87 | TAS1R3 (0.44) | CYP3A4TP53P2RX7GAAMAPT | |
| SCHEMBL7604538 | 0.86 | CYP3A4 (0.49) | CYP3A4ALDH1A1TP53GPBAR1CNR2 | |
| SCHEMBL14494205 | 0.81 | HDAC6 (0.44) | CYP3A4ALDH1A1GPBAR1UTS2RHPGD | |
| SCHEMBL9348751 | 0.81 | NPC1 (0.43) | CYP3A4ALDH1A1TP53GPBAR1CNR2 | |
| SCHEMBL9350175 | 0.78 | TRPM8 (0.46) | ALDH1A1CNR2MEN1KMT2ARAB9A | |
| SCHEMBL9348811 | 0.78 | TAS1R3 (0.40) | CYP3A4ALDH1A1CNR2UTS2RHPGD | |
| SCHEMBL7605909 | 0.76 | GPBAR1 (0.46) | CYP3A4ALDH1A1TDP1GPBAR1UTS2R | |
| SCHEMBL7605876 | 0.76 | TP53 (0.42) | CYP3A4ALDH1A1TP53GPBAR1HPGD | |
| SCHEMBL5313373 | 0.76 | GAA (0.40) | TP53GPBAR1MEN1POLBKMT2A | |
| SCHEMBL9349033 | 0.76 | LMNA (0.39) | ALDH1A1TP53HPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |