Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989875 | 0.88 | TSHR (0.40) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL20305332 | 0.83 | LMNA (0.41) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL5410864 | 0.77 | TSHR (0.50) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL23989741 | 0.77 | TSHR (0.40) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL1004738 | 0.76 | HPGD (0.40) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL162971 | 0.76 | TSHR (0.48) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL23991169 | 0.76 | CA12 (0.49) | TSHRALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL13506034 | 0.75 | KMT2A (0.45) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL5275787 | 0.74 | TSHR (0.47) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL23062875 | 0.74 | TAS1R3 (0.33) | KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125414-B2 | Pyridine derivatives compounds for controlling invertebrate pests | BASF SE (DE) | 2015-09-08 | — | — | US | disclosed |
| US-8710056-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2451808-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-20120122681-A1 | Pyridine Derivatives Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2451808-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| WO-2011003793-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
| EP-1517897-A2 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS | Pfizer Products Inc. (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | CHESWORTH RICHARD (US) | 2004-01-01 | — | — | US | disclosed |
| WO-2004000817-A2 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122681-A1 | Pyridine Derivatives Compounds for Controlling Invertebrate Pests | PRXL2A, GRIN2A, CNR2 | TSHR 2414/4885ALDH1A1 1692/4885KDM4E 2096/4885 |
| US-20120110705-A1 | Pyridazine Compounds for Controlling Invertebrate Pests | CNR2, GRIN2C, GRIN2A | TSHR 996/4885ALDH1A1 2558/4885KDM4E 3229/4885 |
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | ESR1, GPER1, ESR2 | TSHR 300/4885ALDH1A1 581/4885KDM4E 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.