Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349115 | 0.80 | ATP4A (0.66) | — | |
| SCHEMBL9265136 | 0.80 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL9652797 | 0.77 | ATP4A (0.50) | — | |
| SCHEMBL9506558 | 0.76 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL9510106 | 0.76 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL9267772 | 0.75 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL774957 | 0.74 | ATP4A (0.61) | — | |
| SCHEMBL9723911 | 0.73 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL10499291 | 0.73 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL9272003 | 0.71 | MEN1 (0.47) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416749-B1 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT (NL) | 1994-08-17 | — | — | EP | disclosed |
| US-5082841-A | Enzyme inhibitor | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1992-01-21 | — | — | US | disclosed |
| EP-0416749-A2 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-03-13 | — | — | EP | disclosed |