⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042768 | 0.98 | — | — | |
| SCHEMBL16652572 | 0.78 | — | — | |
| SCHEMBL899641 | 0.78 | HPGD (0.33) | — | |
| SCHEMBL98197 | 0.78 | — | — | |
| SCHEMBL23081736 | 0.78 | HPGD (0.33) | — | |
| SCHEMBL10709604 | 0.75 | — | — | |
| SCHEMBL23407903 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL590033 | 0.74 | — | — | |
| SCHEMBL11210270 | 0.73 | ADH1A (0.35) | — | |
| SCHEMBL96545 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061188-B | A kind of preparation method of 4,4 difiuorocyclohexyl formic acid | 艾琪康医药科技（上海）有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-105061188-A | Preparation method of 4,4-difluorocyclohexanecarboxylic acid | SHANGHAI AQBIOPHARMA CO LTD | 2015-11-18 | — | — | CN | claimed |
| WO-2008132128-A2 | SYNTHESIS OF A PHARMACEUTICALLY ACTIVE COMPOUND | Solvay (Société Anonyme) (BE) | 2008-11-06 | — | — | WO | claimed |
| EP-4727934-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| EP-4720062-A1 | PYRIDO[3,4-D]PYRIMIDIN-4-ONE AND PYRIMIDO[5,4-D]PYRIMIDIN-4-ONE DERIVATIVES AS TREM2 AGONISTS FOR THE TREATMENT OF PARKINSON'S DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-12583820-B2 | Broad spectrum antivirals against coronavirus | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2026-03-24 | — | — | US | disclosed |
| WO-2025064788-A2 | CCR5 CONJUGATES AND USES THEREOF | CIDARA THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2024260929-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024246019-A1 | PYRIDO[3,4-D]PYRIMIDIN-4-ONE AND PYRIMIDO[5,4-D]PYRIMIDIN-4-ONE DERIVATIVES AS TREM2 AGONISTS FOR THE TREATMENT OF PARKINSON'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | disclosed |
| US-11981657-B2 | Substituted benzimidazoles, their preparation and their use as pharmaceuticals | EPIGENETIX, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-05-18 | — | — | US | disclosed |
| EP-1490336-A1 | PIPERIDINE OR 8-AZA-BICYCLO(3.2.1)OCT-3-YL DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY (ESPECIALLY CCR5) | AstraZeneca AB (SE) | 2004-12-29 | — | — | EP | disclosed |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| WO-2003080574-A1 | PIPERIDINE OR 8-AZA-BICYCLO[3.2.1]OCT-3-YL DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY (ESPECIALLY CCR5) | ASTRAZENECA AB (SE) | 2003-10-02 | — | — | WO | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1112268-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015633-A1 | CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-23 | — | — | WO | disclosed |
| US-5840704-A | INSECTICIDES, MITICIDES, ANTHELMINTICS | PFIZER INC. (US) | 1998-11-24 | — | — | US | disclosed |
| US-5451511-A | Biosynthesis, avermectins | PFIZER INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5089480-A | ANTIPARASITIC AGENTS | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |