Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98197 | 1.00 | — | — | |
| SCHEMBL23081736 | 1.00 | HPGD (0.33) | HPGD | |
| SCHEMBL10709604 | 0.97 | — | — | |
| SCHEMBL8456551 | 0.88 | — | — | |
| SCHEMBL96545 | 0.87 | — | — | |
| SCHEMBL9238 | 0.87 | — | — | |
| SCHEMBL11210270 | 0.87 | ADH1A (0.35) | — | |
| SCHEMBL13447535 | 0.87 | HPGD (0.31) | HPGD | |
| SCHEMBL160292 | 0.86 | EPHX2 (0.32) | — | |
| SCHEMBL19968817 | 0.86 | EPHX2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250391519-A1 | CHEMICAL SYNTHESIS PLATFORM | UNIV GLASGOW COURT (GB) | 2025-12-25 | — | — | US | disclosed |
| US-12358868-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20230406816-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA INC (US) | 2023-12-21 | — | — | US | disclosed |
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| CN-110872230-B | Preparation method of 1- (trifluoromethyl) cyclopropane-1-carboxylic acid compound and intermediate thereof | 浙江九洲药业股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA, INC. | 2022-06-02 | — | — | US | disclosed |
| CN-110872230-A | Preparation method and intermediate of 1- (trifluoromethyl) cyclopropane-1-carboxylic acid compound | 浙江九洲药业股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-104870446-B | Substituted pyrimidinyl and pyridinyl-pyrrolopyridinones, process for their preparation and their use as kinase inhibitors | 内尔维阿诺医学科学有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-109476940-A | Active energy ray curable resin for printing ink, active energy ray curable ink composition, active energy ray curable ink and cured film | 哈利玛化成株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-108472242-A | Pharmaceutical composition for treating cancer | 埃克塞里艾克西斯公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-106488768-A | Methods of treating lung adenocarcinoma | 埃克塞里艾克西斯公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-104788372-A | Deuterated cabozantinib derivative, preparation method and application thereof, and intermediate of deuterated cabozantinib derivative | SHANGHAI SHENGKAO MEDICAL TECHNOLOGY CO LTD | 2015-07-22 | — | — | CN | disclosed |
| US-20140066444-A1 | Method of Treating Cancer | EXELIXIS, INC. (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140057908-A1 | Method of Treating Cancer | EXELIXIS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| EP-2621482-A1 | DUAL INHIBITORS OF MET AND VEGF FOR THE TREATMENT OF CASTRATION RESISTANT PROSTATE CANCER AND OSTEOBLASTIC BONE METASTASES | Exelixis, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130197230-A1 | METHODS OF PREPARING QUINOLINE DERIVATIVES | EXELIXIS, INC. | 2013-08-01 | — | — | US | disclosed |
| WO-2012044574-A1 | DUAL INHIBITORS OF MET AND VEGF FOR THE TREATMENT OF CASTRATION RESISTANT PROSTATE CANCER AND OSTEOBLASTIC BONE METASTASES | EXELIXIS, INC. (US) | 2012-04-05 | — | — | WO | disclosed |
| EP-2350011-A1 | METHODS OF PREPARING QUINOLINE DERIVATIVES | Exelixis, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010056960-A1 | METHODS OF PREPARING QUINOLINE DERIVATIVES | EXELIXIS INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-4826773-A | AMMONIUM MOLYBDATE; PHOTOMETRY | HOFFMANN-LA ROCHE INC. (US) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197230-A1 | METHODS OF PREPARING QUINOLINE DERIVATIVES | F12, RECQL, H1-2 | HPGD 1608/4885 |
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | HPGD 222/4885 |
| US-12358868-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | HPGD 222/4885 |
| US-20140066444-A1 | Method of Treating Cancer | MET, HGF, ACP3 | HPGD 2411/4885 |
| US-20250391519-A1 | CHEMICAL SYNTHESIS PLATFORM | SET, CBS, COASY | HPGD 3120/4885 |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | HPGD 222/4885 |
| US-20230406816-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | HPGD 222/4885 |
| US-20140057908-A1 | Method of Treating Cancer | MET, HGF, ACP3 | HPGD 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.