⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708258 | 0.83 | — | — | |
| SCHEMBL9179785 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL9685526 | 0.81 | TP53 (0.40) | — | |
| SCHEMBL30946964 | 0.81 | TP53 (0.56) | — | |
| SCHEMBL11292820 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL8674267 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL9530571 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL10597981 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL699113 | 0.78 | — | — | |
| SCHEMBL2141473 | 0.75 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025848-A1 | ZWITTERIONIC COMPOUNDS OF 2-PHOSPHOCHOLINE CARBOXYLIC ACIDS AND THEIR USE AS CYTOTOXIC AGENTS | UNIVERSIDAD DE ALICANTE (ES) | 2020-02-06 | — | — | WO | claimed |
| US-20170210775-A1 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS, INC. | 2017-07-27 | — | — | US | claimed |
| US-9637515-B2 | Guggulphospholipid methods and compositions | JINA PHARMACEUTICALS, INC. (US) | 2017-05-02 | — | — | US | claimed |
| EP-2088865-B1 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC (US) | 2015-10-21 | — | — | EP | claimed |
| US-20100151002-A1 | Guggulphospholipid Methods and Compositions | JINA PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | claimed |
| EP-2088865-A2 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | Jina Pharmaceuticals Inc. (US) | 2009-08-19 | — | — | EP | claimed |
| US-20090202816-A1 | STABILIZED SILICA COLLOID | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-08-13 | — | — | US | claimed |
| WO-2008058156-A9 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008058156-A2 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | claimed |
| WO-2007146680-A1 | STABILIZED SILICA COLLOID | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION , INC. (US) | 2007-12-21 | — | — | WO | claimed |
| US-5811568-A | PHOSPHORYLATION | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-09-22 | — | — | US | claimed |
| WO-1995029923-A1 | PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | claimed |
| EP-0043472-B1 | 3-HYDROCARBYLTHIO-2-ACYLOXYPROPYL 2-TRIMETHYLAMMONIOETHYL PHOSPHATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1983-07-20 | — | — | EP | claimed |
| EP-0043472-A1 | 3-Hydrocarbylthio-2-acyloxypropyl 2-trimethylammonioethyl phosphates, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-01-13 | — | — | EP | claimed |
| US-4163748-A | Propane-1,3-diol phosphatides and method of preparing the same | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1979-08-07 | — | — | US | claimed |
| JP-58164596-A | — | — | None | — | — | JP | disclosed |
| JP-58144394-A | — | — | None | — | — | JP | disclosed |
| US-3960905-A | Diacylglycerophosphoric acid esters of aminoethanol and methylaminoethanol and method of preparing the same | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DT) | 1976-06-01 | — | — | US | disclosed |
| US-3940423-A | SURFACTANTS, EMULSIFIERS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DT) | 1976-02-24 | — | — | US | disclosed |
| US-3940423-A | SURFACTANTS, EMULSIFIERS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DT) | 1976-02-24 | — | — | US | disclosed |