Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597981 | 1.00 | TP53 (0.39) | TP53TDP1LPAR3LPAR2LPAR1 | |
| SCHEMBL11292820 | 1.00 | TP53 (0.39) | TP53TDP1LPAR3LPAR2LPAR1 | |
| SCHEMBL8674267 | 1.00 | TP53 (0.39) | TP53TDP1LPAR3LPAR2LPAR1 | |
| SCHEMBL9685526 | 0.98 | TP53 (0.40) | TP53TDP1LPAR3LPAR2LPAR1 | |
| SCHEMBL10708258 | 0.90 | — | — | |
| SCHEMBL11665213 | 0.86 | LPAR3 (0.35) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL10598471 | 0.86 | LPAR3 (0.35) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL10316593 | 0.84 | TP53 (0.50) | TP53TDP1LPAR3LPAR2LPAR1 | |
| SCHEMBL10598475 | 0.82 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| SCHEMBL93503 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0210804-B1 | PHOSPHATE ESTER DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANKYO COMPANY LIMITED (JP) | 1989-05-10 | — | — | EP | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0210804-A1 | Phosphate ester derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1987-02-04 | — | — | EP | disclosed |